IL17 Mediates Pelvic Pain in Experimental Autoimmune Prostatitis (EAP)
نویسندگان
چکیده
منابع مشابه
IL17 Mediates Pelvic Pain in Experimental Autoimmune Prostatitis (EAP)
Chronic pelvic pain syndrome (CPPS) is the most common form of prostatitis, accounting for 90-95% of all diagnoses. It is a complex multi-symptom syndrome with unknown etiology and limited effective treatments. Previous investigations highlight roles for inflammatory mediators in disease progression by correlating levels of cytokines and chemokines with patient reported symptom scores. It is hy...
متن کاملExperimental autoimmune prostatitis induces chronic pelvic pain.
Pain is the hallmark of patients with chronic prostatitis (CP) and chronic pelvic pain syndrome (CPPS). Despite numerous hypotheses, the etiology and pathogenesis remain unknown. To better understand CP/CPPS, we used a murine experimental autoimmune prostatitis model to examine the development, localization, and modulation of pelvic pain. Pelvic pain was detected 5 days after antigen instillati...
متن کاملThe mediation of interleukin-17 and chemokine ligand 2 in pelvic pain of experimental autoimmune prostatitis
The present study aimed to determine the expression and mediation of interleukin-17 (IL-17) and chemokine ligand 2 (CCL2) in a rat model with experimental autoimmune prostatitis (EAP). A total of 44 Sprague Dawley (SD) rats were used in the present study. Of these, a total of 20 two-month-old SD rats were randomly divided into a normal control (n=10) and a model group (EAP group, n=10). The rem...
متن کامل[Chronic prostatitis and chronic pelvic pain syndrome].
Acute prostatitis is infrequent and is manifested as a severe systemic infection requiring hospitalization. Some of these cases may result in a chronic infection requiring long-term antibiotic courses. However, chronic non-bacterial prostatitis is much more frequent, and as such, it it is frequently underdiagnosed and maltreated. The symptoms are variant and include pain and discomfort in the p...
متن کاملChronic prostatitis/chronic pelvic pain syndrome.
In the 20th century, the term "prostatitis" traditionally referred to inflammation in the prostate, often attributed to infection. Prostatitis in this century usually refers to a chronic pain syndrome for which the presence of inflammation and involvement of the prostate are not always certain. This article discusses chronic prostatitis/chronic pelvic pain syndrome and the various factors assoc...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2015
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0125623